Source:http://linkedlifedata.com/resource/entrezgene/interaction/5879-156110
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 Nef binds and activates Nef-associated kinase via interactions with the small GTPases CDC42 and Rac1, which are required for optimal levels of Nef-dependent viral replication in vivo,
HIV-1 Nef interacts with Rac1 in a protein complex including DOCK2 and ELMO1,
HIV-1 Nef-mediated activation of Vav induces an increase of active Rac1 levels,
Rac1 inhibits HIV-1 Nef-mediated CD80 and CD86 relocation from cell surface to the intracellular compartment
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| entrezgene:keyphrase |
interacts with,
inhibited by,
activates,
Interacts with
|