Source:http://linkedlifedata.com/resource/entrezgene/interaction/5568-155030
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 MA increases phosphorylation and the DNA-binding activity of CREB and c-Myc through activation of the cAMP/PKA and MEK/ERK signaling pathways. Both signaling pathways are synergistically activated upon co-stimulation through the CD19 receptor,
HIV-1 Matrix impairs proliferation of normal lymphocytes in vitro by inducing the activity of the inhibitory protein kinase A (PKA),
Protein kinase A (PKA) has been shown to phosphorylate HIV-1 Matrix in vitro,
cAMP-dependent protein kinase is incorporated into HIV-1 virions, interacts with and phosphorylates the HIV-1 Capsid protein, and regulates HIV-1 infectivity
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| entrezgene:keyphrase |
activates,
phosphorylated by
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