Source:http://linkedlifedata.com/resource/entrezgene/interaction/3105-155971
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed |
pubmed-article:10546855,
pubmed-article:10799863,
pubmed-article:11932387,
pubmed-article:12427289,
pubmed-article:1316930,
pubmed-article:17116886,
pubmed-article:20200278,
pubmed-article:2789433,
pubmed-article:7539755,
pubmed-article:7913356,
pubmed-article:8084338,
pubmed-article:8671651,
pubmed-article:8877415,
pubmed-article:9120272,
pubmed-article:9263011,
pubmed-article:9373217
|
| entrezgene:interactant | |
| entrezgene:geneRifText |
Conformational changes in HIV-1 gp120, including an enhanced expression of the V3 loop of gp120 and of epitopes that are exposed upon CD4 binding, are consistent with the formation of a multimolecular complex between HLA class I and gp120/160,
Epitope Env37-46 from HIV-1 gp160 binds strongly to HLA-A3 molecules and forms very stable complexes,
HIV-1 gp160-derived peptide p18 presented by H-2Dd class I major histocompatibility complex molecules is processed by angiotensin-1 converting enzyme (ACE) prior to T cell stimulation by the peptide p18,
HIV-1 gp41 selectively enhances MHC class I, ICAM-1, IFN-alpha, IFN-beta, and IFN-omega expression in H9 cells,
Soluble HIV-1 gp41 can selectively enhance MHC class I and II expression on human B cells, but does not increase expression of other cell surface antigens such as CD21 and CD54 (ICAM-1),
Soluble HIV-1 gp41 enhancement effects on MHC class I and II antigen expression can be inhibited by soluble gp41-binding proteins of 45, 49 and 62 kD from human B cells,
Treatment of CD4+ T cells with HIV-1 gp120 significantly increases CD4 association with CD3, CD45RA, CD45RB, CD59, CD38, CD26 and HLA class I, and decreases that with CD45RC
|
| entrezgene:keyphrase |
interacts with,
upregulates,
binds,
complexes with
|