Source:http://linkedlifedata.com/resource/entrezgene/interaction/2353-155871
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
Co-treatment of osteoblastic cells with HIV-1 Tat and RANKL/M-CSF upregulates c-fos expression and AP-1 activity,
HIV-1 Tat activates the AP-1 complex containing c-fos through a p56lck dependent mechanism,
HIV-1 Tat contributes to the super-induction of IL-2 promoter activity through transcription factors such as NF-kappaB and AP-1 (c-Jun and c-Fos),
HIV-1 Tat expression in Jurkat T cells enhances cooperative NFAT/AP-1- but not AP-1-dependent transcription independent of its ability to transactivate the HIV-1 LTR,
HIV-1 Tat upregulates c-Fos expression and c-Fos protein has been shown to be essential for optimal transactivation of the HIV-1 LTR promoter by Tat,
The CKLF-like MARVEL transmembrane domain-containing family 2 (CMTM2) blocks HIV-1 Tat-induced AP-1 and CREB activation, which leads to suppress HIV-1 provirus transcription,
Transcription factors NFAT and AP-1 (c-Jun/c-Fos) are required for HIV-1 Tat-induced upregulation of COX-2
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| entrezgene:keyphrase |
interacts with,
upregulates,
requires,
activates,
enhances
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