Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/156110-925
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 Nef colocalizes with CD8-CD3 zeta on the HEK293 cell surface,
HIV-inoculated and HIV-1 Nef-treated human peripheral blood lymphocytes downregulate cell surface CD8, and this down-modulation could inhibit anti-HIV cytotoxicity associated with cytotoxic T-cell function,
-COP as a cellular cofactor is required for HIV-1 Nef-mediated HLA-A2, CD4, and CD8 downregulation
|
| entrezgene:keyphrase |
downregulates,
colocalizes with
|