Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/156110-5578
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PKC activity and serine 6 in HIV-1 Nef are required for Nef-supported transcription, infectivity, and replication,
Protein kinase C phosphorylates HIV-1 Nef at threonine 15,
Treatment of cells with protein kinase C (PKC) inhibitors reduces HIV-1 Nef phosphorylation in vivo, and phosphorylation of Nef increases 8- to 12-fold after treatment with phorbol myristate acetate; these data indicate PKC phosphorylates Nef
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requires,
phosphorylated by
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