Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/156110-3383
| Predicate | Object |
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
Expression of HIV-1 Nef in macrophages induces the release of sICAM, which upregulates the expression of co-stimulatory receptors on B lymphocytes,
HIV-1 Nef increases the production of exosomes, which form at the plasma membrane and co-localizes with plasma membrane-associated proteins ICAM1, CD81, and Lck in Jurkat,
HIV-1 Nef upregulates ICAM-1 expression on endothelial cells via Erk /Mapk signaling pathway,
Monoclonal antibodies to the cell surface molecule intracellular adhesion molecule (ICAM)-1 inhibit the Nef-induced B-cell differentiation response, suggesting an interaction between Nef and ICAM-1
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| entrezgene:keyphrase |
interacts with,
co-localizes with,
upregulates,
Induces release of
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