Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155971-928
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| entrezgene:geneRifText |
Env-mediated cell-cell fusion repression by CD9 and CD63 requires the presence of HIV-1 Gag. Recruitment of Env to tetraspanin-enriched micro domains (TEMs) is required for cell-cell fusion repression by CD9 and CD63,
Overexpression of CD81 and CD9 renders cells less susceptible to HIV-1 gp120/gp41-mediated syncytia formation; antibodies raised against CD9 and CD81 enhance syncytia formation,
Tetraspanin proteins, such as CD9, CD63, CD81, CD82, and CD231, are incorporated on the membrane of released virions in an HIV-1 envelope protein (Env)-independent manner and have the potential to inhibit HIV-1 Env-mediated infection
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inhibited by
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