Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155971-5788
| Predicate | Object |
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
CD4(+)CD45RO(+) cells display high HIV-1 gp120-binding capacity, whereas CD4(+)CD45RO(-) cells show undetectable HIV-1 gp120 binding,
CD45 modulates HIV-1 gp120-induced apoptosis by regulating Fas ligand induction and activation of the phosphoinositide 3-kinase/Akt pathway,
HIV-1 gp120-induced apoptosis is regulated by CD45 through inducing CD45 association with the HIV coreceptor CXCR4 in T cell lines and peripheral blood mononuclear cells,
Treatment of CD4+ T cells with HIV-1 gp120 significantly increases CD4 association with CD3, CD45RA, CD45RB, CD59, CD38, CD26 and HLA class I, and decreases that with CD45RC
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| entrezgene:keyphrase |
interacts with,
regulated by,
modulated by
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