Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155971-5595
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed |
pubmed-article:10027715,
pubmed-article:10581001,
pubmed-article:11504923,
pubmed-article:11532249,
pubmed-article:12089333,
pubmed-article:12239168,
pubmed-article:12775419,
pubmed-article:15371627,
pubmed-article:15603708,
pubmed-article:15689238,
pubmed-article:16621960,
pubmed-article:17627030,
pubmed-article:17897354,
pubmed-article:17983270,
pubmed-article:19319745,
pubmed-article:20842205,
pubmed-article:22028271,
pubmed-article:22039051,
pubmed-article:22479424,
pubmed-article:9403476,
pubmed-article:9658081
|
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 X4-tropic gp120 upregulates alpha-SMA (ACTA2) and collagen I alpha 1 expression via the ERK1/2 pathway in a CXCR4-dependent manner in activated human hepatic stellate cells,
HIV-1 gp120 activates c-Jun N-terminal kinase (JNK) and p42 extracellular-regulated kinase (ERK) in macrophages and primary human central nervous system (CNS) cells,
HIV-1 gp120 induces IL-10 expression in monocyte-derived dendritic cells via a mannose C-type lectin receptor and an ERK signaling pathway,
HIV-1 gp120-induced phosphatidylcholine-specific phospholipase D (PLD) activity is dependent on the activation of ERK1/2,
HIV-1 gp41 is able to activate the ERK/MAPK pathway by binding to CD74,
Increased neurotoxicity mediated by cocaine and gp120 involves signaling pathways including c-jun N-terminal kinase (JNK), p38, extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinases (MAPK), and nuclear factor (NF)-kappaB,
NHERF1 increases ERK1/2 phosphorylation levels following HIV-1 gp120 stimulation in cells,
Pre-treatment of endothelial cells with fibroblast growth factor 2 (FGF2) protects cells from HIV-1 gp120 angiotoxicity; this protection is regulated by crosstalk among the ERK, PI3K-AKT and PKC signaling pathways,
Stimulation of human monocyte-derived macrophages with HIV-1 gp120 results in the CCR5-mediated activation of Lyn and the concomitant Lyn-dependent activation of the mitogen-activated protein (MAP) kinase ERK-1/2, which leads to production of TNF-alpha,
The activation of mitogen-activated protein kinases (MAPKs, including ERK, JNK, and p38MAPK) is induced by incubation of HIV-1 gp160 with CD4+complement receptor type 2 (CR2)+ cells,
Treatment of cells with HIV-1 gp120 induces increased levels of endogenous c-fos and c-jun mRNA and proteins, an activation of both c-fos and c-jun promoters, and a very rapid stimulation of the MAPK/ERK pathway
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| entrezgene:keyphrase |
induces phosphorylation of,
regulated by,
stimulates,
activates
|