Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155971-5304
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| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
Binding of HIV-1 envelope protein gp120 to CD4 downregulates Bcl-2 expression; this effect is inhibited by gp17/GCDFP-15, which blocks the ability of CD4 to interact with gp120, leading to moderate up-regulation of Bcl-2,
Gross cystic disease fluid protein-15 (GCDFP-15) binds to CD4, a T-cell co-receptor involved in antigen recognition, thereby inhibiting the ability of the receptor to interact with the HIV-1 envelope protein gp120
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| entrezgene:keyphrase |
inhibited by
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