Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155971-3689
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Anti-CD18 monoclonal antibodies completely block cell fusion between HIV-1 infected U-937 cells and MT-4 T cells, indicating participation of CD18, or of the protein complex CD11a-c/CD18, in addition to CD4, in the infection and cytopathic effect of HIV-1,
HIV-1 gp120 is identified to have a physical interaction with integrin, beta 2 (ITGB2) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses,
HIV-1 gp120-mediated ICAM-1 expression has functional significance, as it enhances the ability of monocytic cells to bind to gp120-stimulated human astrocytes in an ICAM-1/beta 2 integrin-dependent fashion,
HIV-1 gp160 is identified to have a physical interaction with integrin, beta 2 (ITGB2) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses
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interacts with
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