Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155971-1236
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 gp120 interactions with CXCR4 and CCR5 lead to the cross-desensitization of CCR6 and CCR7; this gp120-induced inhibition is strictly dependent on CXCR4 or CCR5 and lipid rafts but not on CD4 or V(H)3-expressing BCR,
Stimulated HIV-1 infected CD4+ cells induce plasmacytoid dendritic cell (PDC) activation and maturation in a manner that is inhibited by antibodies to HIV-1 gp120; markers for PDC migration (CCR7) are enhanced during this process
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| entrezgene:keyphrase |
inhibits,
upregulates
|