Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155908-1460
| Predicate | Object |
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
CK2 modulates the interaction of Rev with nucleolar phosphoprotein B23 by phosphorylating B23,
CK2 phosphorylates Rev on Serine 5 and Serine 8,
HIV-1 Rev interacting protein, casein kinase 2 beta polypeptide (CSNK2B), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with CSNK2B is decreased by RRE,
Rev activates CK2, an effect hypothesized to promote HIV-1 replication,
amino acids 35-50 of Rev are involved with electrostatic interactions with CK2 while amino acids 12-24 of Rev are involved with hydrophobic interactions,
phosphorylation of Rev is dependent on the beta subunit of CK2
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| entrezgene:keyphrase |
interacts with,
binds,
activates,
modulated by,
phosphorylated by
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