Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155871-836
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed |
pubmed-article:10602513,
pubmed-article:10799874,
pubmed-article:11509621,
pubmed-article:15179054,
pubmed-article:15204919,
pubmed-article:17967742,
pubmed-article:18074388,
pubmed-article:18092356,
pubmed-article:18551626,
pubmed-article:19812265,
pubmed-article:20340172,
pubmed-article:21483469,
pubmed-article:22216281,
pubmed-article:22629415,
pubmed-article:9878167
|
| entrezgene:interactant | |
| entrezgene:geneRifText |
A p53 fusion protein with the HIV-1 Tat basic domain at its N terminus activates the expression of p21and downregulates the levels of caspase-3 and Bcl-2,
Co-administration of morphine and HIV-1 Tat significantly increases the percentage of neurons expressing active caspase-3,
HIV-1 Tat induces apoptosis through activation of caspase-3,
HIV-1 Tat-induced apoptosis through increased expression of anti-apoptotic protein Bcl-2, proapoptotic protein Bax and activation of caspases CASP3 and CASP9 is inhibited by estrogen receptor beta (ER)-mediated estrogen treatment,
PDGF-BB prevents caspase-3 activation induced by HIV-1 Tat and morphine in neuroblastoma cells,
Tat-triggered PKCdelta and PKCtheta activation results in the downstream signaling through the apoptosis pathways mediated by both ERK1/2 and caspase-3,
The levels of caspase-3 protein are reduced after Caco-2 cells exposure to HIV-1 Tat compared with control
|
| entrezgene:keyphrase |
downregulates,
interacts with,
upregulates,
modulates,
activates
|