Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155871-1803
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 Tat induces tyrosine phosphorylation of DPPIV in Tat/DPPIV-coexpressing cells,
HIV-1 Tat inhibits the enzymatic activity of CD26, thereby suppressing DNA synthesis and IL-1 beta production, stimulating secretion of IL-1 receptor antagonist and TNF-alpha, and causing, at least in part, the immunosuppressive effects of Tat,
HIV1-Tat co-localizes and coimmunoprecipitates with human Dipeptidyl peptidase IV (DPPIV) protein,
The N-terminal nine amino acids of HIV-1 Tat mediate the binding of Tat to CD26
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| entrezgene:keyphrase |
inhibits,
induces phosphorylation of,
co-localizes with,
binds
|