Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155871-1051
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 Tat induces an increase in C/EBPbeta binding activity through a direct binding interaction between Tat and C/EBPbeta that is mediated through the N-terminal, cysteine rich, and core regions of Tat (amino acids 1-47),
HIV-1 Tat induces iNOS in human astroglia through the activation of NF-kappaB and C/EBPbeta, an effect that may participate in the pathogenesis of HIV-associated dementia,
HIV-1 Tat upregulates IL-6 expression by transactivating the IL-6 promoter, an effect mediated through enhancement of CAAT enhancer-binding protein (C/EBP; nuclear factor-IL-6) DNA binding activity,
Interaction between TGF-beta signaling proteins Smad-3 and Smad-4, and C/EBPbeta modulates basal and HIV-1 Tat-mediated transcription of the HIV-1 LTR promoter in astrocytes,
Interaction of C/EBPbeta and HIV-1 Tat stimulates MCP-1 transcription in astrocytes,
Specific C/EBP and NF-kappaB transcription factor binding elements within the IL-1beta promoter are involved in Tat regulation of IL-1beta production,
Tat-C/EBPbeta association is mediated through cdk9, which phosphorylates C/EBPbeta,
The synergistic interaction between C/EBP-2 and Tat with the subtype C LTR is observed in U-937 cells
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| entrezgene:keyphrase |
interacts with,
cooperates with,
binds,
associates with,
activates,
modulated by
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