Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155871-1026
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| entrezgene:interactant | |
| entrezgene:geneRifText |
A p53 fusion protein with the HIV-1 Tat basic domain at its N terminus activates the expression of p21and downregulates the levels of caspase-3 and Bcl-2,
HIV-1 Tat inhibits SIRT1 and increases acetylation of p53, which leads to activation of p21 and BAX in HeLa-CD4+ cells
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| entrezgene:keyphrase |
activates
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