Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155807-920
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| rdf:type | |
| entrezgene:pubmed | |
| entrezgene:interactant | |
| entrezgene:geneRifText |
HIV-1 Nef-Vpr fusion proteins are efficiently incorporated into HIV-1 particles and possess CD4 downregulation activity in target cells,
HIV-1 Vpr downregulates the expression of surface CD4 receptors in Jurkat T cells,
HIV-1 Vpr increases expression of Nef protein from integrase-defective HIV-1. The Vpr-mediated expression of Nef from IN-minus HIV-1 results in CD4 downregulation
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| entrezgene:keyphrase |
downregulates
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