Source:http://linkedlifedata.com/resource/entrezgene/hivinteraction/155348-23633
| Predicate | Object |
|---|---|
| rdf:type | |
| entrezgene:pubmed |
pubmed-article:10366569,
pubmed-article:10525473,
pubmed-article:10888652,
pubmed-article:11035935,
pubmed-article:11278458,
pubmed-article:11389849,
pubmed-article:12368302,
pubmed-article:12414950,
pubmed-article:15037073,
pubmed-article:1631159,
pubmed-article:22928108,
pubmed-article:9275210,
pubmed-article:9366553
|
| entrezgene:interactant | |
| entrezgene:geneRifText |
Karyopherin alpha and beta are reported to interact with HIV-1 integrase (IN) to facilitate nuclear import of IN, however a conflicting report indicates nuclear accumulation of IN does not involve karyopherin alpha, beta 1, or beta 2 mediated pathways,
Karyopherin alpha binds to a bipartite nuclear localization signal in HIV-1 integrase (amino acids 186-189 and 211-219),
Some reports indicate a possible role for the interactions between karyopherin alpha and beta with HIV-1 integrase in the nuclear import of HIV-1 preintegration complexes (PIC), while other reports indicate integrase is not involved in PIC nuclear import
|
| entrezgene:keyphrase |
binds,
imported by
|