Source:http://linkedlifedata.com/resource/#_5131303732360014
Predicate | Object |
---|---|
rdf:type | |
uniprot:attribution | |
rdf:subject | |
rdf:predicate | |
rdf:object |
Potently and reversibly inhibits the insect voltage-gated Shaker (Sh) potassium channel (isoform alpha (B)), the mammalian voltage-gated potassium channels Kv1.2/KCNA2. Its effect on Kv1.3/KCNA3 is controversial, since this channel is voltage-independently inhibited in PubMed:9464266, but is not affected in PubMed:10931199. Furthermore, this toxin competes with apamin (a small conductance calcium-activated potassium channel inhibitor) for binding onto rat brain synaptosomes.
|