Source:http://linkedlifedata.com/resource/#_503532383530001E
| Predicate | Object |
|---|---|
| rdf:type | |
| uniprot:attribution | |
| rdf:subject | |
| rdf:predicate | |
| rdf:object |
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate.
|