Source:http://linkedlifedata.com/resource/#_503332333534001E
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rdf:type | |
uniprot:attribution |
http://linkedlifedata.com/resource/#_503332333534001F,
http://linkedlifedata.com/resource/#_5033323335340020,
http://linkedlifedata.com/resource/#_5033323335340021,
http://linkedlifedata.com/resource/#_5033323335340022,
http://linkedlifedata.com/resource/#_5033323335340023,
http://linkedlifedata.com/resource/#_5033323335340024,
http://linkedlifedata.com/resource/#_5033323335340025,
http://linkedlifedata.com/resource/#_5033323335340026
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rdf:subject | |
rdf:predicate | |
rdf:object |
Required for DNA synthesis. Required for entry into or completion of S phase. Involved in DNA replication and seems to participate in the activation of the pre-replication complex (pre-RC) and in transcription elongation. May play a role as a key coordinator in assembling the replication fork. Proposed to function at replication origins following the binding of the MCM2-7 complex prior to the recruitment of CDC45. Probably is required to stimulate phosphorylation of the MCM2-7 complex by the CDC7-DBF4 kinase complex. May recruit the DNA polymerase alpha:primase complex to replication origins and is required to maintain it on chromatin independently of CDC45. May also play a role in transcriptional silencing.
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