| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses. SUBUNIT: Homodimer, and heterodimer of GMEB1 and GMEB2. GMEB1 and GMEB2 form the parvovirus initiator complex (PIF). Interacts with the glucocorticoid receptor (NR3C1) and NCOA2/TIF2 (By similarity). May interact with HSP27 and CREB-binding protein (CBP). SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=May be also cytoplasmic. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y692-1; Sequence=Displayed; Name=2; IsoId=Q9Y692-2; Sequence=VSP_005970; SIMILARITY: Contains 1 SAND domain. GENE SYNONYMS:GMEB1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 573 AA; 62591 MW; 8175B0730F1550B8 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:4370,
urn:biopax:RelationshipXref:NCBI GENE_10691,
urn:biopax:RelationshipXref:REFSEQ_NP_006573,
urn:biopax:RelationshipXref:REFSEQ_NP_077808,
urn:biopax:UnificationXref:UNIPROT_B1AT48,
urn:biopax:UnificationXref:UNIPROT_Q9NWH1,
urn:biopax:UnificationXref:UNIPROT_Q9UKD0,
urn:biopax:UnificationXref:UNIPROT_Q9Y692
|
| biopax3:displayName |
GMEB1_HUMAN
|
| biopax3:name |
DNA-binding protein p96PIF,
GMEB-1,
GMEB1,
PIF p96,
Parvovirus initiation factor p96
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED
|
| biopax3:standardName |
Glucocorticoid modulatory element-binding protein 1
|