| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity). CATALYTIC ACTIVITY: GDP-beta-L-fucose + N(4)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl- (1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D- glucosaminyl)asparagine = GDP + N(4)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl- (1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-(alpha-L-fucosyl- (1->6))-N-acetyl-beta-D-glucosaminyl)asparagine. PATHWAY: Protein modification; protein glycosylation. SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (By similarity). Note=Membrane-bound form in trans cisternae of Golgi (By similarity). SIMILARITY: Belongs to the glycosyltransferase 23 family. SIMILARITY: Contains 1 SH3 domain. WEB RESOURCE: Name=Functional Glycomics Gateway - GTase; Note=Fucosyltransferase 8; URL="http://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_mou_615"; GENE SYNONYMS:Fut8. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 575 AA; 66557 MW; 226092A8959B3EB7 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:1858901,
urn:biopax:RelationshipXref:NCBI GENE_53618,
urn:biopax:RelationshipXref:REFSEQ_NP_001239543,
urn:biopax:RelationshipXref:REFSEQ_NP_001239544,
urn:biopax:RelationshipXref:REFSEQ_NP_001239545,
urn:biopax:RelationshipXref:REFSEQ_NP_058589,
urn:biopax:UnificationXref:UNIPROT_Q543F5,
urn:biopax:UnificationXref:UNIPROT_Q921U1,
urn:biopax:UnificationXref:UNIPROT_Q9WTS2
|
| biopax3:displayName |
FUT8_MOUSE
|
| biopax3:name |
2.4.1.68,
Fucosyltransferase 8,
Fut8,
GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase,
GDP-fucose--glycoprotein fucosyltransferase,
Glycoprotein 6-alpha-L-fucosyltransferase,
alpha1-6FucT
|
| biopax3:organism | |
| biopax3:sequence |
MRAWTGSWRWIMLILFAWGTLLFYIGGHLVRDNDHPDHSSRELSKILAKLERLKQQNEDLRRMAESLRIPEGPIDQGTATGRVRVLEEQLVKAKEQIENYKKQARNGLGKDHEILRRRIENGAKELWFFLQSELKKLKHLEGNELQRHADEILLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPLAVPEDLADRLLRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPTLLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAVYPHKPRTEEEIPMEPGDIIGVAGNHWDGYSKGINRKLGKTGLYPSYKVREKIETVKYPTYPEAEK
|
| biopax3:standardName |
Alpha-(1,6)-fucosyltransferase
|