| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
SEQUENCE 699 AA; 78151 MW; 23C4413B10F641BA CRC64;,
SUBUNIT: Forms a complex with BECN1, PIK3C3 and PIK3R4. A subpopulation of these complexes also harbor KIAA0226/Rubicon. UVRAG-containing complexes never including ATG14, both forming mutually exclusive complexes with BECN1 through direct competition. SUBCELLULAR LOCATION: Late endosome. Lysosome. Early endosome. Note=Colocalizes with RAB9-positive compartments involved in retrograde transport from late endosomes to trans-Golgi network. Colocalization with early endosomes is only partial. TISSUE SPECIFICITY: Highly expressed in brain, lung, kidney and liver. DISEASE: Note=A chromosomal aberration involving UVRAG has been observed in a patient with heterotaxy (left-right axis malformation). Inversion Inv(11)(q13.5;q25). SIMILARITY: Contains 1 C2 domain. SEQUENCE CAUTION: Sequence=CAA67507.1; Type=Erroneous gene model prediction; GENE SYNONYMS:UVRAG. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| biopax3:xref | |
| biopax3:displayName |
UVRAG_HUMAN
|
| biopax3:name |
UVRAG,
p63
|
| biopax3:entityFeature |
urn:biopax:ModificationFeature:UVRAG_HUMAN_1,
urn:biopax:ModificationFeature:UVRAG_HUMAN_10,
urn:biopax:ModificationFeature:UVRAG_HUMAN_11,
urn:biopax:ModificationFeature:UVRAG_HUMAN_12,
urn:biopax:ModificationFeature:UVRAG_HUMAN_13,
urn:biopax:ModificationFeature:UVRAG_HUMAN_2,
urn:biopax:ModificationFeature:UVRAG_HUMAN_3,
urn:biopax:ModificationFeature:UVRAG_HUMAN_4,
urn:biopax:ModificationFeature:UVRAG_HUMAN_5,
urn:biopax:ModificationFeature:UVRAG_HUMAN_6,
urn:biopax:ModificationFeature:UVRAG_HUMAN_7,
urn:biopax:ModificationFeature:UVRAG_HUMAN_8,
urn:biopax:ModificationFeature:UVRAG_HUMAN_9
|
| biopax3:organism | |
| biopax3:sequence |
MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIEWKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGREVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSELSYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFMEHGLMVRCDRHHTSSAIPVPKRQSSIFGGADVGFSGGIPSPDKGHRKRASSENERLQYKTPPPSYNSALAQPVTTVPSMGETERKITSLSSSLDTSLDFSKENKKKGEDLVGSLNGGHANVHPSQEQGEALSGHRATVNGTLLPSEQAGSASVQLPGEFHPVSEAELCCTVEQAEEIIGLEATGFASGDQLEAFNCIPVDSAVAVECDEQVLGEFEEFSRRIYALNENVSSFRRPRRSSDK
|
| biopax3:standardName |
UV radiation resistance-associated gene protein
|