| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways. SUBCELLULAR LOCATION: Secreted (By similarity). Note=Found in the nasal mucus (By similarity). Apical side of airway epithelial cells. Detected in nasal mucus (By similarity). TISSUE SPECIFICITY: Lung, upper airways and nasopharyngeal regions, including trachea and nasal epithelium. Specifically expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. Highest expression in the trachea and progressive decrease from proximal (bronchial) to distal (bronchiolar) airways. Also expressed in lung cancers and some other types of cancer. INDUCTION: By all-trans retinoic acid (ATRA). PTM: May be N-glycosylated. MISCELLANEOUS: Binds lipopolysaccharides. SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. Plunc family. GENE SYNONYMS:BPIFA1 LUNX NASG PLUNC SPURT. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 256 AA; 26713 MW; EDF152FBC35315BC CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:15749,
urn:biopax:RelationshipXref:NCBI GENE_51297,
urn:biopax:RelationshipXref:REFSEQ_NP_001230122,
urn:biopax:RelationshipXref:REFSEQ_NP_057667,
urn:biopax:RelationshipXref:REFSEQ_NP_570913,
urn:biopax:UnificationXref:UNIPROT_A8K9R3,
urn:biopax:UnificationXref:UNIPROT_E1P5M9,
urn:biopax:UnificationXref:UNIPROT_Q9NP55,
urn:biopax:UnificationXref:UNIPROT_Q9NZT0
|
| biopax3:displayName |
BPIA1_HUMAN
|
| biopax3:name |
BPIFA1,
Lung-specific protein X,
Nasopharyngeal carcinoma-related protein,
Palate lung and nasal epithelium clone protein,
Secretory protein in upper respiratory tracts,
Tracheal epithelium-enriched protein,
Von Ebner protein Hl
|
| biopax3:organism | |
| biopax3:sequence |
MFQTGGLIVFYGLLAQTMAQFGGLPVPLDQTLPLNVNPALPLSPTGLAGSLTNALSNGLLSGGLLGILENLPLLDILKPGGGTSGGLLGGLLGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQVNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGILNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIKV
|
| biopax3:standardName |
BPI fold-containing family A member 1
|