| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro- dihydrosphingosine, D-erythro-sphingosine and L-threo- dihydrosphingosine. Binds phosphoinositides (By similarity). CATALYTIC ACTIVITY: ATP + sphinganine = ADP + sphinganine 1- phosphate. CATALYTIC ACTIVITY: ATP + sphingosine = ADP + sphingosine 1- phosphate. COFACTOR: Magnesium (By similarity). SUBCELLULAR LOCATION: Lysosome membrane (By similarity). SIMILARITY: Contains 1 DAGKc domain. GENE SYNONYMS:Sphk2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 617 AA; 65618 MW; 40EE2C2C288BE26A CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:1861380,
urn:biopax:RelationshipXref:NCBI GENE_56632,
urn:biopax:RelationshipXref:REFSEQ_NP_001166032,
urn:biopax:RelationshipXref:REFSEQ_NP_064395,
urn:biopax:RelationshipXref:REFSEQ_NP_975009,
urn:biopax:UnificationXref:UNIPROT_Q91VA9,
urn:biopax:UnificationXref:UNIPROT_Q9DBH6,
urn:biopax:UnificationXref:UNIPROT_Q9JIA7
|
| biopax3:displayName |
SPHK2_MOUSE
|
| biopax3:name |
2.7.1.91,
SK 2,
SPK 2,
Sphk2
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MAPPPLLPVAASTPILHGEFGSYPANGPRFALTLTTQALHIQRLRPKPEARPRDGLVSLDEVSGCGTLQSRSPEDTAAYFCIYTYPRGRRGGRRRATRTFRADGATTYEENRAEAQRWATALTCLLRGVPLSGDQEITPELLPRKPRLLILVNPFGGRGLAWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGLSLSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVRMPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGSRCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPGSPEPLPDLSLNGGGPELTGDWGGAGDAPLSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGFLPPTHSAPEASTWGPVDHLLPPLGSPLPQDWVTIEGEFVLMLGILPSHLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLGCPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTGPAGQKPQA
|
| biopax3:standardName |
Sphingosine kinase 2
|