Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). SUBUNIT: Heterodimer with uroplakin-1B (UPK1B). SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (Potential). Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9BT76-1; Sequence=Displayed; Name=2; IsoId=Q9BT76-2; Sequence=VSP_037327; SIMILARITY: Belongs to the uroplakin-3 family. SEQUENCE CAUTION: Sequence=AAO89507.1; Type=Frameshift; Positions=210; Sequence=AAS07526.1; Type=Erroneous gene model prediction; GENE SYNONYMS:UPK3B. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 320 AA; 33882 MW; 64A1FE268A8BB0EB CRC64;
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biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:21444,
urn:biopax:RelationshipXref:NCBI GENE_80761,
urn:biopax:RelationshipXref:REFSEQ_NP_085047,
urn:biopax:RelationshipXref:REFSEQ_NP_872625,
urn:biopax:UnificationXref:UNIPROT_A8K231,
urn:biopax:UnificationXref:UNIPROT_A8MZA8,
urn:biopax:UnificationXref:UNIPROT_B3KPU5,
urn:biopax:UnificationXref:UNIPROT_Q75MM5,
urn:biopax:UnificationXref:UNIPROT_Q86W06,
urn:biopax:UnificationXref:UNIPROT_Q9BT76
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biopax3:displayName |
UPK3B_HUMAN
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biopax3:name |
UP3b,
UPIIIb,
UPK3B,
Uroplakin IIIb,
p35
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biopax3:organism | |
biopax3:sequence |
MGLPWGQPHLGLQMLLLALNCLRPSLSLGEWGSWMDASSQTQGAGGPAGVIGPWAPAPLRLGEAAPGTPTPVSVAHLLSPVATELVPYTPQITAWDLEGKVTATTFSLEQPRCVFDGLASASDTVWLVVAFSNASRGFQNPETLADIPASPQLLTDGHYMTLPLSPDQLPCGDPMAGSGGAPVLRVGHDHGCHQQPFCNAPLPGPGPYREDPRIHRHLARAAKWQHDRHYLHPLFSGRPPTLGLLGSLYHALLQPVVAGGGPGAAADRLLHGQALHDPPHPTQRGRHTAGGLQAWPGPPPQPQPLAWPLCMGLGEMGRWE
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biopax3:standardName |
Uroplakin-3b
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