| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
SEQUENCE 957 AA; 99369 MW; 4C5CDF5E6656A675 CRC64;,
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix. Cytoplasm. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q96P44-1; Sequence=Displayed; Name=2; IsoId=Q96P44-2; Sequence=VSP_031083, VSP_031085, VSP_031086; Note=No experimental confirmation available; Name=3; IsoId=Q96P44-3; Sequence=VSP_031084; Note=No experimental confirmation available; TISSUE SPECIFICITY: Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes. Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium. DEVELOPMENTAL STAGE: Highest expression observed at the fetal stage. Expressed by smooth-muscle cells in the artery wall in a PDGF-dependent way. INDUCTION: Stimulated by PDGF/platelet-derived growth factor. SIMILARITY: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. SIMILARITY: Contains 7 collagen-like domains. SIMILARITY: Contains 1 laminin G-like domain. SIMILARITY: Contains 1 VWFA domain. SEQUENCE CAUTION: Sequence=AAH45597.1; Type=Frameshift; Positions=478; GENE SYNONYMS:COL21A1 COL1AL. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:17025,
urn:biopax:RelationshipXref:NCBI GENE_81578,
urn:biopax:RelationshipXref:REFSEQ_NP_110447,
urn:biopax:UnificationXref:UNIPROT_A6NIX5,
urn:biopax:UnificationXref:UNIPROT_B2R8J9,
urn:biopax:UnificationXref:UNIPROT_Q49A51,
urn:biopax:UnificationXref:UNIPROT_Q71RF4,
urn:biopax:UnificationXref:UNIPROT_Q8WXV8,
urn:biopax:UnificationXref:UNIPROT_Q96P44,
urn:biopax:UnificationXref:UNIPROT_Q9H0V3
|
| biopax3:displayName |
COLA1_HUMAN
|
| biopax3:name |
COL21A1
|
| biopax3:organism | |
| biopax3:sequence |
MAHYITFLCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRFLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQLSPKKIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPNY
|
| biopax3:standardName |
Collagen alpha-1(XXI) chain
|