| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: May play a role in apoptosis. Isoform 1 seems to be the main initiator. SUBUNIT: Interacts with MCL1, BCL2, BCL2L1/BCL-Xl, BCL2A1 and BCL2L2/BCL-w. Interacts with the myosin V actin motor complex through its binding to DLC2 (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=BMF-I; IsoId=Q96LC9-1; Sequence=Displayed; Name=2; Synonyms=BMF-II; IsoId=Q96LC9-2; Sequence=VSP_012292; Name=3; Synonyms=BMF-III; IsoId=Q96LC9-3; Sequence=VSP_012293, VSP_012294; TISSUE SPECIFICITY: Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells. SIMILARITY: Belongs to the Bcl-2 family. SEQUENCE CAUTION: Sequence=AAH60783.1; Type=Erroneous initiation; Sequence=BAB15762.1; Type=Erroneous initiation; GENE SYNONYMS:BMF. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 184 AA; 20508 MW; 21479B25CC727853 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:24132,
urn:biopax:RelationshipXref:NCBI GENE_90427,
urn:biopax:RelationshipXref:REFSEQ_NP_001003940,
urn:biopax:RelationshipXref:REFSEQ_NP_001003942,
urn:biopax:RelationshipXref:REFSEQ_NP_001003943,
urn:biopax:RelationshipXref:REFSEQ_NP_277038,
urn:biopax:UnificationXref:UNIPROT_Q2M396,
urn:biopax:UnificationXref:UNIPROT_Q6NT30,
urn:biopax:UnificationXref:UNIPROT_Q6NT56,
urn:biopax:UnificationXref:UNIPROT_Q6P9F6,
urn:biopax:UnificationXref:UNIPROT_Q7Z7D4,
urn:biopax:UnificationXref:UNIPROT_Q7Z7D5,
urn:biopax:UnificationXref:UNIPROT_Q96LC9,
urn:biopax:UnificationXref:UNIPROT_Q9H7K7
|
| biopax3:displayName |
BMF_HUMAN
|
| biopax3:name |
BMF
|
| biopax3:organism | |
| biopax3:sequence |
MEPSQCVEELEDDVFQPEDGEPVTQPGSLLSADLFAQSLLDCPLSRLQLFPLTHCCGPGLRPTSQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAVLPIGEQPPEGQWQHQAEVQIARKLQCIADQFHRLHVQQHQQNQNRVWWQILLFLHNLALNGEENRNGAGPR
|
| biopax3:standardName |
Bcl-2-modifying factor
|