| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: May be involved in the transcriptional activation of MDM2 and EP300 genes. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein family. SIMILARITY: Contains 7 C2H2-type zinc fingers. SIMILARITY: Contains 1 KRAB domain. SIMILARITY: Contains 1 SCAN box domain. GENE SYNONYMS:ZKSCAN4 ZNF307 ZNF427. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 545 AA; 61579 MW; CCFB6B5D976926ED CRC64;
|
| biopax3:xref | |
| biopax3:displayName |
ZKSC4_HUMAN
|
| biopax3:name |
P373c6.1,
ZKSCAN4,
Zinc finger protein 307,
Zinc finger protein 427
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MAREPRKNAALDAQSAEDQTGLLTVKVEKEEASALTAEVRAPCSPARGPERSRQRFRGFRYPEAAGPREALSRLRELCGQWLQPEMHSKEQILELLVLEQFLTILPGNLQSWVREQHPESGEEVVVLLEYLERQLDEPAPQVPVGDQGQELLCCKMALLTQTQGSQSSQCQPMKALFKHESLGSQPLHDRVLQVPGLAQGGCCREDAMVASRLTPGSQGLLKMEDVALTLTPGWTQLDSSQVNLYRDEKQENHSSLVSLGGEIQTKSRDLPPVKKLPEKEHGKICHLREDIAQIPTHAEAGEQEGRLQRKQKNAIGSRRHYCHECGKSFAQSSGLTKHRRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFSQSCSLLEHHKIHTGEKPYQCNMCGKAFRRNSHLLRHQRIHGDKNVQNPEHGESWESQGRTESQWENTEAPVSYKCNECERSFTRNRSLIEHQKIHTGEKPYQCDTCGKGFTRTSYLVQHQRSHVGKKTLSQ
|
| biopax3:standardName |
Zinc finger protein with KRAB and SCAN domains 4
|