Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: Required for the uptake of creatine. Plays an important role in supplying creatine to the brain via the blood-brain barrier. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8VBW1-1; Sequence=Displayed; Name=2; IsoId=Q8VBW1-2; Sequence=VSP_012133; Name=3; IsoId=Q8VBW1-3; Sequence=VSP_012132; Note=No experimental confirmation available; SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily. GENE SYNONYMS:Slc6a8 Crt. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 640 AA; 70999 MW; 67D3AAAC591EEA0B CRC64;
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biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:2147834,
urn:biopax:RelationshipXref:NCBI GENE_102857,
urn:biopax:RelationshipXref:REFSEQ_NP_001136281,
urn:biopax:RelationshipXref:REFSEQ_NP_001136282,
urn:biopax:RelationshipXref:REFSEQ_NP_598748,
urn:biopax:UnificationXref:UNIPROT_A2ALM4,
urn:biopax:UnificationXref:UNIPROT_Q80YC9,
urn:biopax:UnificationXref:UNIPROT_Q8K4R3,
urn:biopax:UnificationXref:UNIPROT_Q8R1L0,
urn:biopax:UnificationXref:UNIPROT_Q8VBW1
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biopax3:displayName |
SC6A8_MOUSE
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biopax3:name |
CT1,
Creatine transporter 1,
Slc6a8,
Solute carrier family 6 member 8
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biopax3:entityFeature | |
biopax3:organism | |
biopax3:sequence |
MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPAKGDGPAGLGAPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDVSGGKGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNIVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
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biopax3:standardName |
Sodium- and chloride-dependent creatine transporter 1
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