Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Note=Associated with microtubules. DEVELOPMENTAL STAGE: Expression begins at S phase, accumulates in late S/G2 phase and disappears in G1 phase. INDUCTION: By p53 when exposed to different DNA damaging agents, including gamma irradiation and chemotherapeutic drugs. PTM: Phosphorylated in mitosis. GENE SYNONYMS:Gtse1 B99. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 741 AA; 78751 MW; 1C684D06EE9B7ACB CRC64;
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biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:1352755,
urn:biopax:RelationshipXref:NCBI GENE_29870,
urn:biopax:RelationshipXref:REFSEQ_NP_001162143,
urn:biopax:RelationshipXref:REFSEQ_NP_038910,
urn:biopax:UnificationXref:UNIPROT_O89015,
urn:biopax:UnificationXref:UNIPROT_Q8R080,
urn:biopax:UnificationXref:UNIPROT_Q9CSG9
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biopax3:displayName |
GTSE1_MOUSE
|
biopax3:name |
GTSE-1,
Gtse1,
Protein B99
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biopax3:entityFeature |
urn:biopax:ModificationFeature:GTSE1_MOUSE_1,
urn:biopax:ModificationFeature:GTSE1_MOUSE_10,
urn:biopax:ModificationFeature:GTSE1_MOUSE_11,
urn:biopax:ModificationFeature:GTSE1_MOUSE_12,
urn:biopax:ModificationFeature:GTSE1_MOUSE_13,
urn:biopax:ModificationFeature:GTSE1_MOUSE_14,
urn:biopax:ModificationFeature:GTSE1_MOUSE_15,
urn:biopax:ModificationFeature:GTSE1_MOUSE_16,
urn:biopax:ModificationFeature:GTSE1_MOUSE_17,
urn:biopax:ModificationFeature:GTSE1_MOUSE_2,
urn:biopax:ModificationFeature:GTSE1_MOUSE_3,
urn:biopax:ModificationFeature:GTSE1_MOUSE_4,
urn:biopax:ModificationFeature:GTSE1_MOUSE_5,
urn:biopax:ModificationFeature:GTSE1_MOUSE_6,
urn:biopax:ModificationFeature:GTSE1_MOUSE_7,
urn:biopax:ModificationFeature:GTSE1_MOUSE_8,
urn:biopax:ModificationFeature:GTSE1_MOUSE_9
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biopax3:organism | |
biopax3:sequence |
MDAGSKKEDFLLLEDEKFDFDLSLSSSSTNEDDEVFFGPVGHKERCIAASLDLNRRVPGQPLAPGSGSPCTLSPLTGEKFVEVYKEAHLLALQIESHSRREVAQAATPQNPVNQGKETFVQDSQLKVSLFEKEQKRDRSPMSLKRETFCLPSSRVQPPMGEPQLLASPGLLSSPVSAGPAQTQSNQGLPCSSQPLPRESSTSQPPSQAGPQKRITSKLQPPRALPVRGRNLHLATEKLKKEVPASIQRTKLVNEKGSQSDVLQDKPSTAPDAASREGHPGKRSLPIPGKLGLKKTLLKPPGYTGNLTRKSSTSGSASSLESGVYRSSVAGKAKSSEQRSSIPASGSQRRTSTSKSGRIGPAASRQALPAAPARVFGRQANKADAAQTVAEQPKVPTLSPLTQQPQTPEQRGPRLDPDTETPQLNKTVSIKRRDSYLSCKTEAVSTTTNPFKVPQFSVGESPGGVTPKFSRTHRLQSWTPASRVVSSTPVRRSSGTTPQGLPGSMRTPLSTRRMSVLPTPASRRLSSLPLMAPQSMPRALVSPLCVPARRLSSEPRRRSTVRAELTQESSGSGSGGQAQGLSSDESSSPPSSVPQALNFSPEKSASPPPQGSSTGAAQGEAEPPEDTLPSEVHGGGCSHTPSEGLLLDLKLDQLTITPEAGGRDLADCPLIDFSNTPESNTALGPSSWPLIDLIMNTPDMGRNDVGKPAKAELGQLIDLGSPLIQLSPEADKENVDSPLLKF
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biopax3:standardName |
G2 and S phase-expressed protein 1
|