| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity). CATALYTIC ACTIVITY: ATP + a carboxylate + CoA = AMP + diphosphate + an acyl-CoA. COFACTOR: Magnesium or manganese (By similarity). ENZYME REGULATION: Activated by monovalent cations, such as potassium, rubidium or ammonium (By similarity). SUBUNIT: Monomer (By similarity). SUBCELLULAR LOCATION: Mitochondrion matrix (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8K0L3-1; Sequence=Displayed; Name=2; IsoId=Q8K0L3-2; Sequence=VSP_028393; Note=No experimental confirmation available; Name=3; IsoId=Q8K0L3-3; Sequence=VSP_028394; Note=No experimental confirmation available; SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family. GENE SYNONYMS:Acsm2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 575 AA; 64269 MW; A7E5956D54B119D8 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:2385289,
urn:biopax:RelationshipXref:NCBI GENE_233799,
urn:biopax:RelationshipXref:REFSEQ_NP_001171448,
urn:biopax:RelationshipXref:REFSEQ_NP_001171449,
urn:biopax:RelationshipXref:REFSEQ_NP_666309,
urn:biopax:UnificationXref:UNIPROT_Q3TNC6,
urn:biopax:UnificationXref:UNIPROT_Q3US47,
urn:biopax:UnificationXref:UNIPROT_Q8K0L3,
urn:biopax:UnificationXref:UNIPROT_Q8R1L3,
urn:biopax:UnificationXref:UNIPROT_Q96LX4
|
| biopax3:displayName |
ACSM2_MOUSE
|
| biopax3:name |
6.2.1.2,
Acsm2,
Acyl-CoA synthetase medium-chain family member 2,
Butyrate--CoA ligase 2,
Butyryl-coenzyme A synthetase 2,
Middle-chain acyl-CoA synthetase 2
|
| biopax3:organism | |
| biopax3:sequence |
MHHLWKIPRLFTLWGNEISCRTFHMNIKKLIPIQWGHQEAPAKFNFASDVIDHWASVEKAGKRSSGPALWWMNGSGKEIKWSFRELSEASKQTANVLSGACGLHRGDRVAVVLPRIPEWWLMILGCMRTGLVFMPGTIQMRSSDILYRLQASKARAIVAGDEVAQEVDAVAPDCSFLKIKLLVSENSREGWLNFKALLKEASTIHQCVETESRESAAIYFTSGTSGPPKMAEHSHCSLGIKAKMDAASWTGLSTSDIIWTISDTAWIMNILGAFLEPWVLGACIFVHLLPKFDSQTVLKVLSSYPINTLVGAPIIYRMLLQQDLSSYKFPHLHSCFSGGETLLPETLENWKAKTGLEIREIYGQTETGLICRVSRTMKVKPGYLGTAFAHYDVQVIDEQGNVLPPGKEGDIAIRVKPIWPIGMFSGYVDNPKKTQDNIRGDFWLMGDRGIKDPEGYFHFIGRSDDIINSSGYRIGPSEVENALMEHPAVSETAVISSPDPSRGEVVKAFVVLAPEFLSHDRDQLTKVLQEHVKSVTAPYKYPRKVEFVLDLPKTVTGKIERAKLRAKEWKTSGRA
|
| biopax3:standardName |
Acyl-coenzyme A synthetase ACSM2, mitochondrial
|