| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes (By similarity). SUBUNIT: Homodimer. Each subunit can interact with either RAB7A or RAB34 (By similarity). Interacts with CLN3 (By similarity). SUBCELLULAR LOCATION: Endomembrane system (By similarity). Late endosome membrane (By similarity). Lysosome membrane (By similarity). Cytoplasmic vesicle, phagosome membrane (By similarity). Note=Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes (By similarity). SIMILARITY: Contains 1 RILP-like domain. SEQUENCE CAUTION: Sequence=AAH51502.1; Type=Erroneous initiation; GENE SYNONYMS:Rilp. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 369 AA; 41139 MW; E419D3E6A7D9094C CRC64;
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| biopax3:xref | |
| biopax3:displayName |
RILP_MOUSE
|
| biopax3:name |
Rilp
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MEPRRAAPRLPSQASSSVGAGSAAELVYHLAGALGTELQGLARRFGPDAAAGLVPLVVRALELLEKAAVGPAPDSLQVSAQQAEVELRRLREENQRLRQELGSGPQEERALLRQLKEVTDRQRDELRAHNRDLQRRSQETEALQEQLQRLLLINSELRHKLAAVQTQLRAAQDRERERQIAQDGSSQLAKEQSLEPDAATSDDPVDTQKQPGNLPEAVQCGFSREELKQILQERNELKANVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVKKQRRKIKAKMLGTPEEAESSEDEDGSWLLLSNDKEDVPLVPESRIQNFFGLWYRGETEAPEAETSNPASSSLQKGEETPQQPHLQPVNSPPAPNS
|
| biopax3:standardName |
Rab-interacting lysosomal protein
|