| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: May activate transcription by interacting directly with the X-box (By similarity). SUBUNIT: Homodimer. Heterodimer with RFX2 and RFX3. Binds DNA. SUBCELLULAR LOCATION: Nucleus (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=4; Name=1; Synonyms=RFX4-D, RFX4_v3; IsoId=Q33E94-1; Sequence=Displayed; Name=2; Synonyms=RFX4-C, RFX4_v4; IsoId=Q33E94-2; Sequence=VSP_030243; Name=3; Synonyms=RFX4-A, RFX4_v1; IsoId=Q33E94-3; Sequence=VSP_030242, VSP_030244; Name=4; IsoId=Q33E94-4; Sequence=VSP_030243, VSP_030245, VSP_030246; TISSUE SPECIFICITY: Isoform 4 is testis-specific. Isoform 1 is expressed in brain and gliomas. Isoform 2 and isoform 3 are testis-specific (at protein level). Isoform 1 is expressed in brain (at protein level). Isoform 3 is expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes. SIMILARITY: Belongs to the RFX family. SIMILARITY: Contains 1 RFX-type winged-helix DNA-binding domain. SEQUENCE CAUTION: Sequence=BAB59001.1; Type=Miscellaneous discrepancy; Note=Probable intron retention; Sequence=BAC11288.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAE48237.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAE48238.1; Type=Erroneous initiation; Note=Translation N-terminally extended; GENE SYNONYMS:RFX4. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 735 AA; 83368 MW; 9C2422428B9D7E8B CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:9985,
urn:biopax:RelationshipXref:NCBI GENE_5992,
urn:biopax:RelationshipXref:REFSEQ_NP_001193620,
urn:biopax:RelationshipXref:REFSEQ_NP_115880,
urn:biopax:RelationshipXref:REFSEQ_NP_998759,
urn:biopax:UnificationXref:UNIPROT_A8K5Y0,
urn:biopax:UnificationXref:UNIPROT_B2RDW4,
urn:biopax:UnificationXref:UNIPROT_Q33DW6,
urn:biopax:UnificationXref:UNIPROT_Q33DW7,
urn:biopax:UnificationXref:UNIPROT_Q33E94,
urn:biopax:UnificationXref:UNIPROT_Q33E95,
urn:biopax:UnificationXref:UNIPROT_Q6YM53,
urn:biopax:UnificationXref:UNIPROT_Q8MHQ1,
urn:biopax:UnificationXref:UNIPROT_Q8NC78,
urn:biopax:UnificationXref:UNIPROT_Q8NDF9,
urn:biopax:UnificationXref:UNIPROT_Q8SNA1,
urn:biopax:UnificationXref:UNIPROT_Q96S80,
urn:biopax:UnificationXref:UNIPROT_Q9BXI0
|
| biopax3:displayName |
RFX4_HUMAN
|
| biopax3:name |
RFX4,
Regulatory factor X 4,
Testis development protein NYD-SP10
|
| biopax3:organism | |
| biopax3:sequence |
MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKKEVSKQTVAYSPRSKLGTLLPEFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRKLITQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEVREEIILTEAAAPTPSPVPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRNTHVPSSSVTHRIPVYPHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYAPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPSANTCYTSPSVHSARYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK
|
| biopax3:standardName |
Transcription factor RFX4
|