| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. SUBUNIT: Found in large molecular weight complexes containing CCNL1 and the p110 isoforms of either CDC2L1 or CDC2L2. Interacts with CCNL2 and CPSF6. SUBCELLULAR LOCATION: Nucleus. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Comment=Isoforms, often lacking the RS domain and differentially expressed in fetal tissues, may be involved in modulation of 9G8 function; Name=1; IsoId=Q16629-1; Sequence=Displayed; Name=2; IsoId=Q16629-2; Sequence=VSP_005872, VSP_005873; Name=3; IsoId=Q16629-3; Sequence=VSP_005874, VSP_005875; TISSUE SPECIFICITY: Brain, liver, kidney and lung. PTM: Extensively phosphorylated on serine residues in the RS domain. SIMILARITY: Belongs to the splicing factor SR family. SIMILARITY: Contains 1 CCHC-type zinc finger. SIMILARITY: Contains 1 RRM (RNA recognition motif) domain. GENE SYNONYMS:SRSF7 SFRS7. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 238 AA; 27367 MW; 49136754D9630853 CRC64;
|
| biopax3:xref | |
| biopax3:displayName |
SRSF7_HUMAN
|
| biopax3:name |
SRSF7,
Splicing factor 9G8,
Splicing factor, arginine/serine-rich 7
|
| biopax3:entityFeature |
urn:biopax:ModificationFeature:SRSF7_HUMAN_1,
urn:biopax:ModificationFeature:SRSF7_HUMAN_10,
urn:biopax:ModificationFeature:SRSF7_HUMAN_11,
urn:biopax:ModificationFeature:SRSF7_HUMAN_12,
urn:biopax:ModificationFeature:SRSF7_HUMAN_13,
urn:biopax:ModificationFeature:SRSF7_HUMAN_14,
urn:biopax:ModificationFeature:SRSF7_HUMAN_15,
urn:biopax:ModificationFeature:SRSF7_HUMAN_16,
urn:biopax:ModificationFeature:SRSF7_HUMAN_17,
urn:biopax:ModificationFeature:SRSF7_HUMAN_18,
urn:biopax:ModificationFeature:SRSF7_HUMAN_19,
urn:biopax:ModificationFeature:SRSF7_HUMAN_2,
urn:biopax:ModificationFeature:SRSF7_HUMAN_20,
urn:biopax:ModificationFeature:SRSF7_HUMAN_21,
urn:biopax:ModificationFeature:SRSF7_HUMAN_22,
urn:biopax:ModificationFeature:SRSF7_HUMAN_3,
urn:biopax:ModificationFeature:SRSF7_HUMAN_4,
urn:biopax:ModificationFeature:SRSF7_HUMAN_5,
urn:biopax:ModificationFeature:SRSF7_HUMAN_6,
urn:biopax:ModificationFeature:SRSF7_HUMAN_7,
urn:biopax:ModificationFeature:SRSF7_HUMAN_8,
urn:biopax:ModificationFeature:SRSF7_HUMAN_9
|
| biopax3:organism | |
| biopax3:sequence |
MSRYGRYGGETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGSPRRSASPERMD
|
| biopax3:standardName |
Serine/arginine-rich splicing factor 7
|