| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB. SUBUNIT: One of the 6 subunits forming the core-TFIIH basal transcription factor which associates with the CAK complex composed of CDK7, CCNH/cyclin H and MNAT1 to form the TFIIH basal transcription factor. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7 (By similarity). SUBCELLULAR LOCATION: Nucleus. SIMILARITY: Belongs to the TFB4 family. SEQUENCE CAUTION: Sequence=CAA82909.1; Type=Frameshift; Positions=302; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/gtf2h3/"; GENE SYNONYMS:GTF2H3. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 308 AA; 34378 MW; E739E2176CD6BAA5 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:4657,
urn:biopax:RelationshipXref:NCBI GENE_2967,
urn:biopax:RelationshipXref:REFSEQ_NP_001507,
urn:biopax:UnificationXref:UNIPROT_B2R819,
urn:biopax:UnificationXref:UNIPROT_Q13889,
urn:biopax:UnificationXref:UNIPROT_Q7L0G0,
urn:biopax:UnificationXref:UNIPROT_Q96AT7
|
| biopax3:displayName |
TF2H3_HUMAN
|
| biopax3:name |
BTF2 p34,
Basic transcription factor 2 34 kDa subunit,
GTF2H3,
General transcription factor IIH polypeptide 3,
TFIIH basal transcription factor complex p34 subunit
|
| biopax3:organism | |
| biopax3:sequence |
MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKVSA
|
| biopax3:standardName |
General transcription factor IIH subunit 3
|