| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. SUBUNIT: TFIID and PCAF are composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TBP is not part of TFTC. Component of the PCAF complex, at least composed of TADA2L/ADA2, TADA3L/ADA3, SUPT3H, TAF5L TAF6L, TAF9, TAF10, TAF12 and TRRAP. Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H, TAF2, TAF4, TAF5, GCN5L2/GCN5, TAF10 and TRRAP. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. The STAGA core complex is associated with a subcomplex required for histone deubiquitination composed of ATXN7L3, ENY2 and USP22. Interacts with TAF3. SUBCELLULAR LOCATION: Nucleus. DOMAIN: The [KR]-[STA]-K motif is specifically recognized by the SETD7 methyltransferase. PTM: Monomethylated at Lys-189 by SETD7, leading to increase its affinity for RNA polymerase II. SIMILARITY: Belongs to the TAF10 family. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/taf10/"; GENE SYNONYMS:TAF10 TAF2A TAF2H TAFII30. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 218 AA; 21711 MW; 032ED5CA97EBE411 CRC64;
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| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:11543,
urn:biopax:RelationshipXref:NCBI GENE_6881,
urn:biopax:RelationshipXref:REFSEQ_NP_006275,
urn:biopax:UnificationXref:UNIPROT_O00703,
urn:biopax:UnificationXref:UNIPROT_Q12962,
urn:biopax:UnificationXref:UNIPROT_Q13175,
urn:biopax:UnificationXref:UNIPROT_Q6FH13
|
| biopax3:displayName |
TAF10_HUMAN
|
| biopax3:name |
STAF28,
TAF(II)30,
TAF10,
TAFII-30,
TAFII30,
Transcription initiation factor TFIID 30 kDa subunit
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MSCSGSGADPEAAPASAASAPGPAPPVSAPAALPSSTAAENKASPAGTAGGPGAGAAAGGTGPLAARAGEPAERRGAAPVSAGGAAPPEGAISNGVYVLPSAANGDVKPVVSSTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGTASGSSRSKSKDRKYTLTMEDLTPALSEYGINVKKPHYFT
|
| biopax3:standardName |
Transcription initiation factor TFIID subunit 10
|