| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. SUBUNIT: Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta- type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3). SUBCELLULAR LOCATION: Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Comment=Additional isoforms seem to exist; Name=A; IsoId=Q10567-1; Sequence=Displayed; Name=B; IsoId=Q10567-2; Sequence=VSP_000163; Name=C; IsoId=Q10567-3; Sequence=VSP_000163, VSP_038753; TISSUE SPECIFICITY: Widely expressed. SIMILARITY: Belongs to the adaptor complexes large subunit family. GENE SYNONYMS:AP1B1 ADTB1 BAM22 CLAPB2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 949 AA; 104637 MW; FE1BA762F9318585 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:554,
urn:biopax:RelationshipXref:NCBI GENE_162,
urn:biopax:RelationshipXref:REFSEQ_NP_001118,
urn:biopax:RelationshipXref:REFSEQ_NP_663782,
urn:biopax:UnificationXref:UNIPROT_C9JRD1,
urn:biopax:UnificationXref:UNIPROT_P78436,
urn:biopax:UnificationXref:UNIPROT_Q10567,
urn:biopax:UnificationXref:UNIPROT_Q20WL3
|
| biopax3:displayName |
AP1B1_HUMAN
|
| biopax3:name |
AP1B1,
Adapter-related protein complex 1 subunit beta-1,
Adaptor protein complex AP-1 subunit beta-1,
Beta-1-adaptin,
Beta-adaptin 1,
Clathrin assembly protein complex 1 beta large chain,
Golgi adaptor HA1/AP1 adaptin beta subunit
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPSAFVEGGRGVVHKSLPPRTASSESAESPETAPTGAPPGEQPDVIPAQGDLLGDLLNLDLGPPVSGPPLATSSVQMGAVDLLGGGLDSLMGDEPEGIGGTNFVAPPTAAVPANLGAPIGSGLSDLFDLTSGVGTLSGSYVAPKAVWLPAMKAKGLEISGTFTRQVGSISMDLQLTNKALQVMTDFAIQFNRNSFGLAPATPLQVHAPLSPNQTVEISLPLSTVGSVMKMEPLNNLQVAVKNNIDVFYFSTLYPLHILFVEDGKMDRQMFLATWKDIPNENEAQFQIRDCPLNAEAASSKLQSSNIFTVAKRNVEGQDMLYQSLKLTNGIWVLAELRIQPGNPSCTDLELSLKCRAPEVSQHVYQAYETILKN
|
| biopax3:standardName |
AP-1 complex subunit beta-1
|