| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. SUBUNIT: Found in a pre-mRNA splicing complex with SRSF4/SFRS4, SRSF5/SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN. SUBCELLULAR LOCATION: Nucleus speckle. PTM: Extensively phosphorylated on serine residues in the RS domain. SIMILARITY: Belongs to the splicing factor SR family. SIMILARITY: Contains 2 RRM (RNA recognition motif) domains. GENE SYNONYMS:SRSF4 SFRS4 SRP75. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 494 AA; 56678 MW; 5BBAB917C218C20A CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:10786,
urn:biopax:RelationshipXref:NCBI GENE_6429,
urn:biopax:RelationshipXref:REFSEQ_NP_005617,
urn:biopax:UnificationXref:UNIPROT_Q08170,
urn:biopax:UnificationXref:UNIPROT_Q5VXP1,
urn:biopax:UnificationXref:UNIPROT_Q9BUA4,
urn:biopax:UnificationXref:UNIPROT_Q9UEB5
|
| biopax3:displayName |
SRSF4_HUMAN
|
| biopax3:name |
Pre-mRNA-splicing factor SRP75,
SRP001LB,
SRSF4,
Splicing factor, arginine/serine-rich 4
|
| biopax3:entityFeature |
urn:biopax:ModificationFeature:SRSF4_HUMAN_1,
urn:biopax:ModificationFeature:SRSF4_HUMAN_10,
urn:biopax:ModificationFeature:SRSF4_HUMAN_11,
urn:biopax:ModificationFeature:SRSF4_HUMAN_12,
urn:biopax:ModificationFeature:SRSF4_HUMAN_13,
urn:biopax:ModificationFeature:SRSF4_HUMAN_14,
urn:biopax:ModificationFeature:SRSF4_HUMAN_2,
urn:biopax:ModificationFeature:SRSF4_HUMAN_3,
urn:biopax:ModificationFeature:SRSF4_HUMAN_4,
urn:biopax:ModificationFeature:SRSF4_HUMAN_5,
urn:biopax:ModificationFeature:SRSF4_HUMAN_6,
urn:biopax:ModificationFeature:SRSF4_HUMAN_7,
urn:biopax:ModificationFeature:SRSF4_HUMAN_8,
urn:biopax:ModificationFeature:SRSF4_HUMAN_9
|
| biopax3:organism | |
| biopax3:sequence |
MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS
|
| biopax3:standardName |
Serine/arginine-rich splicing factor 4
|