Q05707

FUNCTION: Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors (By similarity). SUBUNIT: Homotrimer (By similarity). SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; Synonyms=Undulin 1, Un1; IsoId=Q05707-1; Sequence=Displayed; Name=2; IsoId=Q05707-2; Sequence=VSP_051654; Name=3; Synonyms=Undulin 2, Un2; IsoId=Q05707-3; Sequence=VSP_051653; PTM: Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates (By similarity). PTM: Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains (By similarity). PTM: May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding (By similarity). SIMILARITY: Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. SIMILARITY: Contains 4 collagen-like domains. SIMILARITY: Contains 8 fibronectin type-III domains. SIMILARITY: Contains 1 laminin G-like domain. SIMILARITY: Contains 2 VWFA domains. SEQUENCE CAUTION: Sequence=AAA36795.1; Type=Miscellaneous discrepancy; Sequence=AAH14640.1; Type=Frameshift; Positions=1047; GENE SYNONYMS:COL14A1 UND. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License., SEQUENCE 1796 AA; 193515 MW; 30A72F6E2CC07F70 CRC64;

COEA1_HUMAN

urn:biopax:ModificationFeature:COEA1_HUMAN_1, urn:biopax:ModificationFeature:COEA1_HUMAN_10, urn:biopax:ModificationFeature:COEA1_HUMAN_11, urn:biopax:ModificationFeature:COEA1_HUMAN_12, urn:biopax:ModificationFeature:COEA1_HUMAN_13, urn:biopax:ModificationFeature:COEA1_HUMAN_14, urn:biopax:ModificationFeature:COEA1_HUMAN_15, urn:biopax:ModificationFeature:COEA1_HUMAN_16, urn:biopax:ModificationFeature:COEA1_HUMAN_17, urn:biopax:ModificationFeature:COEA1_HUMAN_18, urn:biopax:ModificationFeature:COEA1_HUMAN_19, urn:biopax:ModificationFeature:COEA1_HUMAN_2, urn:biopax:ModificationFeature:COEA1_HUMAN_20, urn:biopax:ModificationFeature:COEA1_HUMAN_21, urn:biopax:ModificationFeature:COEA1_HUMAN_22, urn:biopax:ModificationFeature:COEA1_HUMAN_23, urn:biopax:ModificationFeature:COEA1_HUMAN_24, urn:biopax:ModificationFeature:COEA1_HUMAN_25, urn:biopax:ModificationFeature:COEA1_HUMAN_26, urn:biopax:ModificationFeature:COEA1_HUMAN_27, urn:biopax:ModificationFeature:COEA1_HUMAN_28, urn:biopax:ModificationFeature:COEA1_HUMAN_29, urn:biopax:ModificationFeature:COEA1_HUMAN_3, urn:biopax:ModificationFeature:COEA1_HUMAN_30, urn:biopax:ModificationFeature:COEA1_HUMAN_31, urn:biopax:ModificationFeature:COEA1_HUMAN_32, urn:biopax:ModificationFeature:COEA1_HUMAN_33, urn:biopax:ModificationFeature:COEA1_HUMAN_34, urn:biopax:ModificationFeature:COEA1_HUMAN_35, urn:biopax:ModificationFeature:COEA1_HUMAN_36, urn:biopax:ModificationFeature:COEA1_HUMAN_37, urn:biopax:ModificationFeature:COEA1_HUMAN_38, urn:biopax:ModificationFeature:COEA1_HUMAN_39, urn:biopax:ModificationFeature:COEA1_HUMAN_4, urn:biopax:ModificationFeature:COEA1_HUMAN_40, urn:biopax:ModificationFeature:COEA1_HUMAN_41, urn:biopax:ModificationFeature:COEA1_HUMAN_42, urn:biopax:ModificationFeature:COEA1_HUMAN_43, urn:biopax:ModificationFeature:COEA1_HUMAN_44, urn:biopax:ModificationFeature:COEA1_HUMAN_45, urn:biopax:ModificationFeature:COEA1_HUMAN_46, urn:biopax:ModificationFeature:COEA1_HUMAN_5, urn:biopax:ModificationFeature:COEA1_HUMAN_6, urn:biopax:ModificationFeature:COEA1_HUMAN_7, urn:biopax:ModificationFeature:COEA1_HUMAN_8, urn:biopax:ModificationFeature:COEA1_HUMAN_9

MKIFQRKMRYWLLPPFLAIVYFCTIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELITFVCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKDALVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKTLTYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASANITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDLPHSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQGPSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGPPGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQLIQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPGTPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAYGVRAPHPDQPEFTPVQDELEAMELWGPGV