| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. SUBUNIT: Monomer. DOMAIN: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines. SIMILARITY: Belongs to the metallothionein superfamily. Type 1 family. GENE SYNONYMS:MT1H. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 61 AA; 6039 MW; 03D866E4F437A2CC CRC64;
|
| biopax3:xref | |
| biopax3:displayName |
MT1H_HUMAN
|
| biopax3:name |
MT-0,
MT-1H,
MT-IH,
MT1H,
Metallothionein-0,
Metallothionein-IH
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MDPNCSCEAGGSCACAGSCKCKKCKCTSCKKSCCSCCPLGCAKCAQGCICKGASEKCSCCA
|
| biopax3:standardName |
Metallothionein-1H
|