| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single- stranded DNA. SUBUNIT: Interacts with RBM42 and ZIK1 (By similarity). Identified in the spliceosome C complex. Interacts with ANKRD28. Interacts with HCV core protein. Interacts with ASFV p30 protein. Interacts with DDX1. SUBCELLULAR LOCATION: Cytoplasm. Nucleus, nucleoplasm. Note=In case of ASFV infection, there is a shift in the localization which becomes predominantly nuclear. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=P61978-1, Q07244-1; Sequence=Displayed; Name=2; IsoId=P61978-2, Q07244-2; Sequence=VSP_002822; Name=3; IsoId=P61978-3; Sequence=VSP_021669, VSP_002822; Note=No experimental confirmation available; PTM: Arg-296 and Arg-299 are dimethylated, probably to asymmetric dimethylarginine. MASS SPECTROMETRY: Mass=50976.25; Method=MALDI; Range=1-463 (P61978-1); Source=PubMed:11840567; SIMILARITY: Contains 3 KH domains. SEQUENCE CAUTION: Sequence=BAD92799.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; GENE SYNONYMS:HNRNPK HNRPK. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 463 AA; 50976 MW; 0F70EE169B2A064A CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:5044,
urn:biopax:RelationshipXref:NCBI GENE_3190,
urn:biopax:RelationshipXref:REFSEQ_NP_002131,
urn:biopax:RelationshipXref:REFSEQ_NP_112552,
urn:biopax:RelationshipXref:REFSEQ_NP_112553,
urn:biopax:UnificationXref:UNIPROT_P61978,
urn:biopax:UnificationXref:UNIPROT_Q07244,
urn:biopax:UnificationXref:UNIPROT_Q15671,
urn:biopax:UnificationXref:UNIPROT_Q59F98,
urn:biopax:UnificationXref:UNIPROT_Q5T6W4,
urn:biopax:UnificationXref:UNIPROT_Q60577,
urn:biopax:UnificationXref:UNIPROT_Q922Y7,
urn:biopax:UnificationXref:UNIPROT_Q96J62
|
| biopax3:displayName |
HNRPK_HUMAN
|
| biopax3:name |
HNRNPK,
TUNP,
Transformation up-regulated nuclear protein,
hnRNP K
|
| biopax3:entityFeature |
urn:biopax:ModificationFeature:HNRPK_HUMAN_1,
urn:biopax:ModificationFeature:HNRPK_HUMAN_10,
urn:biopax:ModificationFeature:HNRPK_HUMAN_11,
urn:biopax:ModificationFeature:HNRPK_HUMAN_2,
urn:biopax:ModificationFeature:HNRPK_HUMAN_3,
urn:biopax:ModificationFeature:HNRPK_HUMAN_4,
urn:biopax:ModificationFeature:HNRPK_HUMAN_5,
urn:biopax:ModificationFeature:HNRPK_HUMAN_6,
urn:biopax:ModificationFeature:HNRPK_HUMAN_7,
urn:biopax:ModificationFeature:HNRPK_HUMAN_8,
urn:biopax:ModificationFeature:HNRPK_HUMAN_9
|
| biopax3:organism | |
| biopax3:sequence |
METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYSGKFF
|
| biopax3:standardName |
Heterogeneous nuclear ribonucleoprotein K
|