| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. SUBUNIT: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Cell projection. SIMILARITY: Belongs to the actin family. ARP2 subfamily. GENE SYNONYMS:ACTR2 ARP2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 394 AA; 44761 MW; 1BFA6B442ED1A797 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:169,
urn:biopax:RelationshipXref:NCBI GENE_10097,
urn:biopax:RelationshipXref:REFSEQ_NP_001005386,
urn:biopax:RelationshipXref:REFSEQ_NP_005713,
urn:biopax:UnificationXref:UNIPROT_B2RCP5,
urn:biopax:UnificationXref:UNIPROT_D6W5F4,
urn:biopax:UnificationXref:UNIPROT_O15142,
urn:biopax:UnificationXref:UNIPROT_P61160,
urn:biopax:UnificationXref:UNIPROT_Q96C82
|
| biopax3:displayName |
ARP2_HUMAN
|
| biopax3:name |
ACTR2,
Actin-like protein 2
|
| biopax3:entityFeature | |
| biopax3:organism | |
| biopax3:sequence |
MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEKLGVTVR
|
| biopax3:standardName |
Actin-related protein 2
|