| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. CATALYTIC ACTIVITY: (3S)-2,3-epoxy-2,3-dihydrosqualene = lanosterol. PATHWAY: Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 3/3. SUBUNIT: Monomer. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. SIMILARITY: Belongs to the terpene cyclase/mutase family. SIMILARITY: Contains 4 PFTB repeats. GENE SYNONYMS:LSS OSC. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 732 AA; 83309 MW; E4708A5AE53585ED CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:6708,
urn:biopax:RelationshipXref:NCBI GENE_4047,
urn:biopax:RelationshipXref:REFSEQ_NP_001001438,
urn:biopax:RelationshipXref:REFSEQ_NP_001138908,
urn:biopax:RelationshipXref:REFSEQ_NP_001138909,
urn:biopax:RelationshipXref:REFSEQ_NP_002331,
urn:biopax:UnificationXref:UNIPROT_D3DSN0,
urn:biopax:UnificationXref:UNIPROT_P48449,
urn:biopax:UnificationXref:UNIPROT_Q8IYL6,
urn:biopax:UnificationXref:UNIPROT_Q9UEZ1
|
| biopax3:displayName |
ERG7_HUMAN
|
| biopax3:name |
2,3-epoxysqualene--lanosterol cyclase,
5.4.99.7,
LSS,
OSC,
Oxidosqualene--lanosterol cyclase,
hOSC
|
| biopax3:organism | |
| biopax3:sequence |
MTEGTCLRRRGGPYKTEPATDLGRWRLNCERGRQTWTYLQDERAGREQTGLEAYALGLDTKNYFKDLPKAHTAFEGALNGMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARIPLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDWLAQRNNVAPDELYTPHSWLLRVVYALLNLYEHHHSAHLRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWYVDGPASTAFQEHVSRIPDYLWMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHHRPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKCPHVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQQRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDGTACAEVSRACDFLLSRQMADGGWGEDFESCEERRYLQSAQSQIHNTCWAMMGLMAVRHPDIEAQERGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPERALAGHP
|
| biopax3:standardName |
Lanosterol synthase
|