| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. SUBUNIT: Interacts with LIN7C (By similarity). SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain. SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily. GENE SYNONYMS:SLC6A12. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 614 AA; 69368 MW; D8FE8D259CE64B62 CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:HGNC_HGNC:11045,
urn:biopax:RelationshipXref:NCBI GENE_6539,
urn:biopax:RelationshipXref:REFSEQ_NP_001116319,
urn:biopax:RelationshipXref:REFSEQ_NP_001116320,
urn:biopax:RelationshipXref:REFSEQ_NP_001193860,
urn:biopax:RelationshipXref:REFSEQ_NP_003035,
urn:biopax:UnificationXref:UNIPROT_A0AV52,
urn:biopax:UnificationXref:UNIPROT_B2R992,
urn:biopax:UnificationXref:UNIPROT_D3DUN8,
urn:biopax:UnificationXref:UNIPROT_P48065
|
| biopax3:displayName |
S6A12_HUMAN
|
| biopax3:name |
BGT-1,
Na(+)/Cl(-) betaine/GABA transporter,
SLC6A12,
Solute carrier family 6 member 12
|
| biopax3:organism | |
| biopax3:sequence |
MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSPTREGLIAGEKETHL
|
| biopax3:standardName |
Sodium- and chloride-dependent betaine transporter
|