| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
FUNCTION: This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. SUBUNIT: Interacts (via N-terminal extracellular domain) with PTHLH and PTH. Homodimer in the absence of bound ligand. Peptide hormone binding leads to dissociation of the homodimer. Interacts (via C-terminus) with the heterodimer formed by GNG2 and GNB1 (By similarity). SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. SIMILARITY: Belongs to the G-protein coupled receptor 2 family. GENE SYNONYMS:Pth1r Pthr Pthr1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 591 AA; 66372 MW; C2E6CCAF2ABAFEEF CRC64;
|
| biopax3:xref |
urn:biopax:RelationshipXref:MOUSE GENOME DATABASE_MGI:97801,
urn:biopax:RelationshipXref:NCBI GENE_19228,
urn:biopax:RelationshipXref:REFSEQ_NP_001077404,
urn:biopax:RelationshipXref:REFSEQ_NP_001077405,
urn:biopax:RelationshipXref:REFSEQ_NP_035329,
urn:biopax:UnificationXref:UNIPROT_P41593,
urn:biopax:UnificationXref:UNIPROT_Q62119,
urn:biopax:UnificationXref:UNIPROT_Q80WU8
|
| biopax3:displayName |
PTH1R_MOUSE
|
| biopax3:name |
PTH/PTHr receptor,
PTH/PTHrP type I receptor,
PTH1 receptor,
Parathyroid hormone 1 receptor,
Pth1r
|
| biopax3:organism | |
| biopax3:sequence |
MGTARIAPSLALLLCCPVLSSAYALVDADDVFTKEEQIFLLHRAQAQCDKLLKEVLHTAANIMESDKGWTPASTSGKPRKEKAPGKFYPESKENKDVPTGSRRRGRPCLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTIFGWGLPAVFVAVWVGVRATLANTGCWDLSSGHKKWIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVFMALPYTEVSGTLWQIQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRAGLSLPLSPRLLPATTNGHSQLPGHAKPGAPAIENETIPVTMTVPKDDGFLNGSCSGLDEEASGSARPPPLLQEEWETVM
|
| biopax3:standardName |
Parathyroid hormone/parathyroid hormone-related peptide receptor
|