Predicate | Object |
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rdf:type | |
biopax3:comment |
FUNCTION: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. PTM: Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. PTM: N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains. SIMILARITY: Belongs to the immunoglobulin superfamily. ICAM family. SIMILARITY: Contains 5 Ig-like C2-type (immunoglobulin-like) domains. WEB RESOURCE: Name=R&D Systems' cytokine source book: ICAM-3; URL="http://www.rndsystems.com/molecule_detail.aspx?m=1589"; WEB RESOURCE: Name=Functional Glycomics Gateway - Glycan Binding; Note=ICAM-3; URL="http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Itlect_263"; GENE SYNONYMS:ICAM3. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
SEQUENCE 547 AA; 59541 MW; 4B7BDC02F24F3031 CRC64;
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biopax3:xref | |
biopax3:displayName |
ICAM3_HUMAN
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biopax3:name |
CD50,
CDw50,
ICAM-3,
ICAM-R,
ICAM3
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biopax3:organism | |
biopax3:sequence |
MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVNLSEPTAHEGSTVTVSCMAGARVQVTLDGVPAAAPGQPAQLQLNATESDDGRSFFCSATLEVDGEFLHRNSSVQLRVLYGPKIDRATCPQHLKWKDKTRHVLQCQARGNPYPELRCLKEGSSREVPVGIPFFVNVTHNGTYQCQASSSRGKYTLVVVMDIEAGSSHFVPVFVAVLLTLGVVTIVLALMYVFREHQRSGSYHVREESTYLPLTSMQPTEAMGEEPSRAE
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biopax3:standardName |
Intercellular adhesion molecule 3
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